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Understanding Cancer Metastasis

Approx. 6 hours to complete

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Course Summary

This course covers the mechanisms and principles of cancer metastasis, including the molecular basis of metastasis, the role of tumor microenvironment, and therapeutic strategies.

Key Learning Points

Gain a comprehensive understanding of the mechanisms and principles of cancer metastasis
Learn about the molecular basis of metastasis and the role of tumor microenvironment
Explore therapeutic strategies to prevent or treat cancer metastasis

Job Positions & Salaries of people who have taken this course might have

- USA: $81,000 - $136,000
- India: INR 586,000 - INR 1,065,000
- Spain: €30,000 - €50,000
- USA: $81,000 - $136,000
- India: INR 586,000 - INR 1,065,000
- Spain: €30,000 - €50,000
- USA: $196,000 - $413,000
- India: INR 1,440,000 - INR 3,040,000
- Spain: €60,000 - €120,000
- USA: $81,000 - $136,000
- India: INR 586,000 - INR 1,065,000
- Spain: €30,000 - €50,000
- USA: $196,000 - $413,000
- India: INR 1,440,000 - INR 3,040,000
- Spain: €60,000 - €120,000
- USA: $65,000 - $122,000
- India: INR 468,000 - INR 876,000
- Spain: €24,000 - €45,000

Learning Outcomes

Understand the molecular basis of cancer metastasis
Learn about the role of tumor microenvironment in cancer metastasis
Gain knowledge of therapeutic strategies for preventing or treating cancer metastasis

Prerequisites or good to have knowledge before taking this course

Basic knowledge of biology and genetics
Familiarity with cancer biology

Course Difficulty Level

Intermediate

Course Format

Online
Self-paced

Similar Courses

Cancer Immunotherapy
Cancer Diagnosis
Cancer Prevention

Related Education Paths

Notable People in This Field

Robert A. Weinberg
Judith Campisi

Related Books

Description

Over 500,000 people in the United States and over 8 million people worldwide are dying from cancer every year. As people live longer, the incidence of cancer is rising worldwide, and the disease is expected to strike over 20 million people annually by 2030.

Everyone has been, or will be touched by cancer in some way during their lifetime. Thanks to years of dedication and commitment to research we’ve made enormous advances in the prevention and treatment of cancer, But there is still a lot of work to be done. In this course, physicians and scientists at the Johns Hopkins School of Medicine explain how cancer spreads or metastasizes. We’ll describe the major theories of metastasis and then describe the biology behind the steps in metastasis. The course also describes the major organs targeted by metastasis and describes how metastases harm the patient.

Outline

History and Overview of Metastasis
Introduction to Understanding Cancer Metastasis
Introduction to History and Overview of Metastasis
History and Overview of Metastasis
History of Metastasis Theory
Introduction to the Sequential Steps of Metastasis
History and Overview of Metastasis

Primary Tumor Growth and Neoangiogenesis
Introduction to Primary Tumor Growth and Neoangiogenesis
Tumor formation: Uncontrolled cell division
The role of mutations in primary tumor formation and evolution
Neoangiogenesis: new blood vessel formation in cancer
The primary tumor microenvironment: what else affects primary tumor growth?
Primary Tumor Growth and Neoangiogenesis

EMT / Invasion / Intravasation
Introduction to EMT / Invasion / Intravasation
Epithelial-mesenchymal transition, invasion, and intravision
Local Tumor Invasion
Intravasation
Invasion and Intravasation

Survival in the Circulation and Extravasation
Introduction to Survival in the Circulation and Extravasation
Glossary of Terms
The Circulation
How cancer cells survive while in circulation
Becoming a circulating tumor cell (CTC) and evading immune detection
Homing to a new site in the body and extravasation
Survival in the Circulation and Extravasation

Dormancy and Secondary Tumor Growth
Introduction to Dormancy and Secondary Tumor Growth
Metastatic homing
Evidence for cancer dormancy
Cancer dormancy defined
Properties of dormant cancer cells
Secondary outgrowth
Dormancy and Secondary Tumor Growth

Morbidity and Mortality Associated with Metastasis
Introduction to Morbidity and Mortality
Distribution of Metastasis: Where do cancers spread?
Cancer Syndromes
Congratulations
Morbidity and Mortality Associated with Metastasis

Summary of User Reviews

Read reviews of the Cancer Metastasis course on Coursera. Users describe the course as informative and engaging. Many users praise the course instructors for their expertise and engaging teaching style.

Key Aspect Users Liked About This Course

The course instructors are highly knowledgeable and engaging.

Pros from User Reviews

The course covers a wide range of topics related to cancer metastasis.
The instructors are highly knowledgeable and engaging.
The course provides practical knowledge that can be applied in real-life situations.
The course materials are well-organized and easy to follow.
The course offers opportunities for students to collaborate and learn from one another.

Cons from User Reviews

Some users find the course content to be too advanced.
A few users have reported technical difficulties with the online platform.
The course may not be suitable for those without a background in biology or medicine.
The course assignments and quizzes can be challenging.
The course requires a significant time commitment.

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